Lysosome-associated membrane glycoprotein 2

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August undefined, 2024

WebGene ID: 118461668, updated on 29-May-2024. Summary Other designations. lysosome-associated membrane glycoprotein 2-like WebPharos : Target Details - LAMP2 Targets Ligands About Tutorials lightbulb feedback Protein Classes help help No PANTHER Classes or DTO Classes found Expression Data (0 Tissues) help help tutorial lightbulb No expression data found Protein Sequence and Structure help help Residue Counts Protein Sequence Find Targets by Sequence search

Crystal structure of the conserved domain of the DC lysosomal ...

Lysosome-associated membrane glycoproteins (LAMPs) are integral membrane proteins, specific to lysosomes, and whose exact biological function is not yet clear. Structurally, the lamp proteins consist of two internally homologous lysosome-luminal domains separated by a proline-rich hinge region; at the C-terminal extremity there is a transmembrane region (TM) followed by a very short cytoplasmic tail (C). In each of the duplicated domains, there are two conserved disulfide bonds. … The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b.When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C-terminal sequence: in the luminal domain, the transmembrane domain, and the cytoplasmic tail. The … See more Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the cell. Some of this is done via acid hydrolases … See more LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of cancerous … See more kirsty weakley lgc

Lysosomal Membrane Proteins and Their Central Role in Physiology

WebLysosome-associated membrane protein-2 gene mutations. The LAMP-2 gene is located on Xq24, while the gene for LAMP-1 is on 13q34. 4 The LAMP-2 open reading frame … WebLAMP2 (Lysosome-associated membrane glycoprotein 2, CD107b) is a member of a family of membrane glycoproteins. LAMP2 provides selectins with carbohydrate ligands, and may play a role in tumor cell metastasis, and have a function in the protection, maintenance, and adhesion of the lysosome. Prior to posttranslational modification, … WebDefects in glycoprotein degradation: E778: Other disorders of glycoprotein metabolism: E779: Disorder of glycoprotein metabolism, unspecified: ... Lysosome-associated membrane protein 2 [LAMP2] deficiency: E7409: Other glycogen storage disease: E7410: Disorder of fructose metabolism, unspecified: E7411: Essential fructosuria: kirsty way trampoline

LAMP2 Gene - GeneCards LAMP2 Protein LAMP2 Antibody

Cell surface membrane lysosome-associated membrane …

WebA lysosome (/ ˈ l aɪ s ə ˌ s oʊ m /) is a membrane-bound organelle found in many animal cells. They are spherical vesicles that contain hydrolytic enzymes that can break down … WebLysosome-associated membrane protein 2 [LAMP2] deficiency: E7409: Other glycogen storage disease: E7410: Disorder of fructose metabolism, unspecified: E7411: Essential … kirsty waylandWebApr 13, 2024 · The CBT-SiPc purity was confirmed by 1 H NMR, HPLC, and HRMS spectra. Resonances at 9.63 and 8.38 ppm were assigned to signals of the phthalocyanine ring with 16 protons. The three resonances at 5.61–5.63, 7.89–7.96, and 8.10–8.12 were designated to the six aromatic protons of chlorophenyl thiophene, while the four sets of resonances … kirsty webeck comedian

"WebFeb 15, 2024 · Lysosome-associated membrane glycoprotein 2 Short names LAMP-2; Lysosome-associated membrane protein 2 Alternative names CD107 antigen-like family member B LGP-110 1 publication LGP-96 1 publication Lysosomal membrane glycoprotein type B ( LGP-B) CD Antigen Name CD107b Gene names Name Lamp2 … " - Lysosome-associated membrane glycoprotein 2

Lysosome-associated membrane glycoprotein 2

Lysosome-associated membrane glycoprotein - Wikipedia

WebMar 21, 2024 · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left Ventricular … WebDec 15, 2000 · Lamp2a acts as a receptor in the lysosomal membrane for substrate proteins of chaperone-mediated autophagy. Using antibodies specific for the cytosolic tail of lamp2a and others recognizing all lamp2 isoforms, we found that in rat liver lamp2a represents 25% of lamp2s in the lysosome.

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WebJan 17, 2024 · lysosomal-associated membrane protein 2 provided by MGI Primary source MGI:MGI:96748 Ensembl:ENSMUSG00000016534 AllianceGenome:MGI:96748 Gene type RefSeq status Organism Lineage Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; … WebFeb 6, 2013 · LIMP-2, also known as SCARB2 belongs to the CD36 family of scavenger receptors 31 and spans the lysosomal membrane twice, with the N- and C-terminus located in the cytosol and a highly glycosylated loop within the lysosomal lumen (Figure 2 ).

WebAug 18, 2024 · For this, we constructed human fibrosarcoma HT1080 cells stably expressing lysosome-associated membrane glycoprotein-1 (LAMP-1) fused to RFP by … WebThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the membrane …

WebFuruno K, Ishikawa T, Akasaki K et al. Morphological localization of a major lysosomal membrane glycoprotein in the endocytic membrane system. J Biochem 1989;106:708–16. ... Silverstein RL, Febbraio M. Identification of lysosome-associated membrane protein-2 as an activation-dependent platelet surface glycoprotein. Blood 1992; 80:1470–75. WebLysosome-associated membrane protein (LAMP2) cardiomyopathy is an X-linked and highly progressive myocardial storage disorder associated with diminished survival, …

WebNov 21, 2016 · 1 CD68 shares structural similarities with lysosomal-associated membrane proteins (LAMPs) and belongs to the LAMP family of glycoproteins. 2 Along with CD68, that is otherwise called LAMP-4, the ...

WebThe LAMP2 gene is located on the Xq24 chromosome. Lysosome-associated membrane protein-2 (LAMP2), together with LAMP1, comprises a major protein component of … kirsty wellsWebBLAST of Lysosome-associated membrane glycoprotein 2 vs. UniProt/SwissProt Match: sp P11438 LAMP1_MOUSE (Lysosome-associated membrane glycoprotein 1 OS=Mus musculus OX=10090 GN=Lamp1 PE=1 SV=2) HSP 1 Score: 65.0846 bits (157), Expect = … lyrics to smoking and drinkingWebLysosome-associated membrane glycoprotein 2A LAMP2A up- or downregulation, and its presence or absence in the lysosomal membrane, enhances or decreases CMA activity, respectively. 34 , 35 The LAMP2A mRNA transcript is generated from alternative splicing of lysosome-associated membrane glycoprotein 2 ( LAMP2 ) pre-mRNA; this splicing … lyrics to smugglers bluesWebJan 1, 2024 · Lysosome-associated membrane glycoprotein 2 (LAMP-2) is a target protein for glycosylation by N-acetylglucosaminyltransferase IV (GnT-IV), which … lyrics to smoke two jointsWebNov 28, 2024 · Peak areas of 4 formerly N-glycosylated peptides, belonging to 4 distinct glycoproteins (Adipocyte plasma membrane-associated protein, Periostin, Cathepsin D, and Lysosome-associated membrane glycoprotein 2) turned out to be significantly increased in subjects affected by PCa compared to controls (Fig. 4). lyrics to smoke on the water by deep purpleWebOct 16, 2015 · Lysosome-associated membrane glycoprotein (LAMP) – preliminary study on a hidden antigen target for vaccination against schistosomiasis Sujeevi S. K. … lyrics to smokestack lightningWebLAMP-2 (Lysosome-associated membrane protein 2) is a single-pass type I membrane protein that belongs to a family of membrane glycoproteins (~40 KDa). LAMP-2 protein is encoded by nine exons, with the first 8 exons and a portion of exon 9 encoding the highly glycosylated protein domains within the lysosomal lumen. lyrics to smooth like butter