WebFeb 21, 2024 · Mammalian body temperature oscillates with the time of the day and is altered in diverse pathological conditions. We recently identified a body temperature-sensitive thermometer-like kinase, which alters SR protein phosphorylation and thereby globally controls alternative splicing (AS). AS can generate mRNA variants containing … WebNov 1, 2024 · Alternative splicing (AS) strongly increases proteome diversity and functionality in eukaryotic cells. Protein secretion is a tightly-controlled process, especially in a tissue-specific and differentiation-dependent manner. While previous work has focussed on transcriptional and posttranslational regulatory mechanisms, the impact of AS on the …
PSF controls expression of histone variants and cellular viability in ...
WebMolecular Cell Article Body Temperature Cycles Control Rhythmic Alternative Splicing in Mammals Marco Preußner,1,* Gesine Goldammer,1 Alexander Neumann,1 Tom Haltenhof,1 Pia Rautenstrauch,1 Michaela Muller-McNicoll,€ 2 and Florian Heyd1 ,3 * 1Laboratory of RNA Biochemistry, Freie Universit€at Berlin, Institute of Chemistry and … WebHeyd Group - RNA Biochemistry. In our work we address the fundamental question how alternative splicing regulates cellular function and identity. Our main model systems are … pop up football tent
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WebManager. I like airports. I love travelling, discovering and immersing in new cultures. That’s why I take time during business trips and consumer immersions to really observe, meet … WebApr 3, 2024 · Scientists in Cambridge and Berlin – including biochemist Professor Florian Heyd – have made an important step in understanding and treating neurodegeneration by using a form of gene therapy to increase levels of cold shock protein in the brains of mice, protecting them against the potentially devastating impact of prion disease, which can … WebApr 11, 2024 · Das Team um Wissenschaftler Florian Heyd von der Freien Universität Berlin entwickelte nun einen vielversprechenden Wirkstoff. Dieser wurde bereits an Mäusen getestet und schützte bei den Versuchstieren vor neurodegenerativen Erkrankungen wie Demenz. ... Heyd und sein Team konzentrierten sich auf das RBM3-Gen, das bei … sharon lucas